(N/A) Glucose is the favoured substrate for respiration.
All carbohydrates are usually first converted into glucose before they are used for respiration.
Other substrates can also be respired,but they do not enter the respiratory pathway at the first step.
As shown in the figure,fats need to be broken down into glycerol and fatty acids first.
If fatty acids are to be respired,they are first degraded to acetyl $CoA$ and enter the pathway.
Glycerol enters the pathway after being converted to $PGAL$.
Proteins are degraded by proteases,and the individual amino acids,depending on their structure,enter the pathway at some stage within the Krebs' cycle or as pyruvate or acetyl $CoA$.
Since respiration involves the breakdown of substrates,the respiratory process has traditionally been considered a catabolic process and the respiratory pathway as a catabolic pathway.
However,compounds are also withdrawn from the respiratory pathway for the synthesis of these substrates.
When the organism needs to synthesize fatty acids,acetyl $CoA$ is withdrawn from the respiratory pathway for it.
Similarly,during the breakdown and synthesis of proteins,respiratory intermediates form the link.
Breaking down processes within the living organism is catabolism,and synthesis is anabolism.
Because the respiratory pathway is involved in both anabolism and catabolism,it is better to consider the respiratory pathway as an amphibolic pathway rather than just a catabolic one.